Lathosterol and other noncholesterol sterols during treatment of hypercholesterolemia with lovastatin alone and with cholestyramine or guar gum.

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Lathosterol and other noncholesterol sterols during treatment of hypercholesterolemia with lovastatin alone and with cholestyramine or guar gum.

Sixty-two patients aged 19-64 years with primary hypercholesterolemia (mean level of total cholesterol, 10.8 mmol/l) were treated with 80 mg/day lovastatin (L) alone for 18 weeks and, after randomization to either L + 20 g/day guar gum (L + GG) or L + 16 g/day cholestyramine (L + C) treatments, for an additional 18 weeks. The total cholesterol level declined from baseline by 34% during L and by...

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Rhabdomyolysis due to combined treatment with lovastatin and cholestyramine.

Assistant Professor C CHRYSANTHOPOULOS (Patras Medical School, Patras, Greece) and Professor NICHOLAS KOUNIS (Patras Technological Educational Institute, Patras 26221, Greece) write: We report two cases in which rhabdomyolysis occurred after combined treatment with lovastatin and cholestyramine. Case I-A 31 year old male athlete with type Ila hyperlipidaemia was treated with lovastatin 20 mg tw...

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ژورنال

عنوان ژورنال: Arteriosclerosis and Thrombosis: A Journal of Vascular Biology

سال: 1992

ISSN: 1049-8834

DOI: 10.1161/01.atv.12.7.807